SCHEMBL23569770

SCHEMBL23569770

CCC(=O)N1CCCC1COC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
POLB P06746 1/20 0.39
ACE P12821 3/20 0.37
KDM4E B2RXH2 1/20 0.37
F2 P00734 1/20 0.37
REN P00797 1/20 0.37
LMNA P02545 1/20 0.37
LTA4H P09960 1/20 0.37
MAPT P10636 1/20 0.37
PEPD P12955 1/20 0.37
ALOX15 P16050 1/20 0.37
PTGS1 P23219 1/20 0.37
HTR2A P28223 1/20 0.37
PTGS2 P35354 1/20 0.37
HRH1 P35367 1/20 0.37
THPO P40225 1/20 0.37
PMP22 Q01453 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ACE2 Q9BYF1 1/20 0.37
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13077173 0.85 MEN1 (0.43) POLBMAPTRAB9ANPC1HPGD
SCHEMBL20756690 0.85 DPP4 (0.37) L3MBTL1POLBACEKDM4EF2
SCHEMBL10118348 0.85 NPC1 (0.39) L3MBTL1POLBACEKDM4EF2
SCHEMBL22815872 0.84 HCRTR2 (0.41) L3MBTL1POLBRAB9AHCRTR2
SCHEMBL18458207 0.84 RAB9A (0.41) L3MBTL1POLBACEKDM4EF2
SCHEMBL13040215 0.84 DPP4 (0.42) L3MBTL1POLBACERENRAB9A
SCHEMBL13662567 0.82 ROCK2 (0.46) L3MBTL1POLBRAB9ADPP4NPC1
SCHEMBL10272737 0.82 ROCK2 (0.46) L3MBTL1POLBRAB9ADPP4NPC1
SCHEMBL13040219 0.81 NPC1 (0.39) RAB9ADPP4NPC1HPGDDPP8
SCHEMBL13077755 0.81 NPC1 (0.47) MAPTRAB9ANPC1HPGDCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518994-B2 Artificial single guide RNA and use thereof BONAC CORPORATION (JP) 2022-12-06 US disclosed
US-20210188895-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE, AND PRODUCTION METHOD THEREFOR BONAC CORPORATION (JP) 2021-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188895-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE, AND PRODUCTION METHOD THEREFOR POLRMT, POLL, RNGTT L3MBTL1 807/4885POLB 17/4885ACE 2561/4885
US-11518994-B2 Artificial single guide RNA and use thereof SLIRP, TRDMT1, RNASEL L3MBTL1 34/4885POLB 2346/4885ACE 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.