Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249850 | 0.84 | HSPB1 (0.44) | — | |
| SCHEMBL4440723 | 0.79 | MEN1 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGSLC6A4 | |
| SCHEMBL4439280 | 0.79 | SLC6A4 (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGPTGS1 | |
| SCHEMBL23263221 | 0.75 | ALDH1A1 (0.47) | SLC6A4SCN8ASCN10AHDAC4HDAC2 | |
| SCHEMBL23258770 | 0.74 | PTGS1 (0.46) | PTGS1PTGS2HDAC4 | |
| SCHEMBL4704057 | 0.73 | SLC6A4 (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGSLC6A4 | |
| SCHEMBL17508317 | 0.73 | NPSR1 (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGSLC6A4 | |
| SCHEMBL12725548 | 0.73 | SLC6A4 (0.57) | SLC6A4MRGPRX4 | |
| SCHEMBL23249861 | 0.73 | HSPB1 (0.43) | — | |
| SCHEMBL4437986 | 0.72 | SLC6A4 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | KINESID THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | TXNRD2, TXNRD1, SDHB | PIK3CD 2759/4885PIK3CA 3917/4885PIK3CB 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.