SCHEMBL6114449

SCHEMBL6114449

O=C(O)c1ccc(-c2c(-c3ccccc3)ccc(C(=O)O)c2C(=O)O)cc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.46
ACMSD Q8TDX5 4/20 0.45
HNF4A P41235 3/20 0.45
CDC25B P30305 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MCL1 Q07820 2/20 0.45
DHFR P00374 1/20 0.45
CDC25A P30304 1/20 0.45
ATM Q13315 1/20 0.45
FOLH1 Q04609 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
SOS1 Q07889 1/20 0.43
HIF1A Q16665 1/20 0.43
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9813471 0.94 ACMSD (0.53) PTPN1ACMSDHNF4ACDC25BHSD17B10
SCHEMBL3807758 0.94 ACMSD (0.45) PTPN1ACMSDHNF4ACDC25BHSD17B10
SCHEMBL21486 0.88 HNF4A (0.52) PTPN1ACMSDHNF4ACDC25BATM
SCHEMBL27024028 0.83 HNF4A (0.48) PTPN1ACMSDHNF4ACDC25BHSD17B10
Biphenyl SCHEMBL2775900 0.83 PTPN1 (0.53) PTPN1ACMSDHNF4ACDC25BHSD17B10
SCHEMBL23175100 0.82 AKR1C3 (0.46) HSD17B10MCL1ALDH1A1AKR1C3AKR1C2
SCHEMBL2748060 0.81 HNF4A (0.53) PTPN1ACMSDHNF4ACDC25BATM
SCHEMBL10783606 0.79 FOLH1 (0.54) FOLH1AKR1C3AKR1C2KDM4EFABP4
Ethylenediamine SCHEMBL28403779 0.79 HNF4A (0.44) PTPN1ACMSDHNF4ACDC25BATM
SCHEMBL28515959 0.79 PTPN1 (0.55) PTPN1ACMSDHNF4ACDC25BHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3221525-A None JP disclosed
US-20120126393-A1 RESIN COMPOSITION, MULTILAYER BODY CONTAINING THE SAME, SEMICONDUCTOR DEVICE, AND FILM MITSUI CHEMICALS, INC. (JP) 2012-05-24 US disclosed
US-5626925-A POLYIMIDE ADJUSTMENT FILM CANON KABUSHIKI KAISHA (JP) 1997-05-06 US disclosed
US-5474876-A Carboxyl-containing polymeric precursor of heterocyclic polymer which is stable at high temperatures and soluble in polar solvents, copolymerizable unsaturated tertiary sulfonium salt, photoinitiator, polar aprotic organic solvent BASF LACKE + FARBEN AG (DE) 1995-12-12 US disclosed
US-5464668-A Polyamideimide substrate with naphthalenetetracarboxylic acid and bis(4-aminophenoxyphenyl)alkane monomers CANON KABUSHIKI KAISHA (JP) 1995-11-07 US disclosed
US-5272247-A Polyimide precursor, cured product thereof, and processes for producing them HITACHI, LTD. (JP) 1993-12-21 US disclosed
JP-H03221525-A POLYAMIC ACID, ITS PRODUCTION, POLYIMIDE AND PRODUCTION THEREOF HITACHI CHEM CO LTD 1991-09-30 JP disclosed
EP-0247731-B1 NOVEL PARA- OR META-TERPHENYLTETRACARBOXYLIC ACID, DIANHYDRIDE THEREOF AND PROCESS FOR PREPARING THE SAME Hitachi Chemical Co., Ltd. (JP) 1991-08-21 EP disclosed