Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 6/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126887 | 0.77 | KMT2A (0.45) | TP53TRPA1MAOAMAOBMEN1 | |
| SCHEMBL12304379 | 0.74 | TP53 (0.47) | TP53PIN1ALPLHCAR2CA12 | |
| SCHEMBL9700645 | 0.73 | ALPL (0.46) | TP53PIN1ALPLHCAR2CA12 | |
| Azobenzene SCHEMBL9435350 | 0.69 | ALDH1A1 (0.75) | TRPA1MAOAMAOBMEN1MAPT | |
| Azobenzene SCHEMBL475771 | 0.69 | ALDH1A1 (0.75) | TRPA1MAOAMAOBMEN1MAPT | |
| SCHEMBL726574 | 0.68 | TP53 (1.00) | TP53PIN1ALPLCA12RPA1 | |
| SCHEMBL7878964 | 0.68 | — | — | |
| Azobenzene SCHEMBL182578 | 0.66 | ALDH1A1 (0.92) | TRPA1MAOAMAOBMEN1MAPT | |
| Azobenzene SCHEMBL182577 | 0.66 | ALDH1A1 (0.92) | TRPA1MAOAMAOBMEN1MAPT | |
| Azobenzene SCHEMBL29187231 | 0.65 | TRPA1 (0.86) | TP53TRPA1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308558-A1 | MODULATORS OF FPR1 AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2024-01-24 | — | — | EP | disclosed |