Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 13/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 13/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 13/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 12/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 11/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 11/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 11/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597462 | 0.79 | CSNK2A2 (0.40) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL12748348 | 0.72 | CSNK2A2 (0.60) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL1275907 | 0.72 | ADRA2A (0.50) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL16597426 | 0.72 | CYP1A2 (0.39) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL10508264 | 0.71 | CSNK2A1 (0.51) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP1A2 | |
| SCHEMBL25331893 | 0.71 | PRKAG1 (0.50) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL14037111 | 0.71 | CSNK2A1 (0.39) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL1878010 | 0.71 | KDM4E (0.51) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP1A2 | |
| SCHEMBL2576855 | 0.69 | ALDH1A1 (0.54) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL12748345 | 0.69 | CSNK2A2 (0.52) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146228-A | Deuterated spiro compound crystal form and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024017270-A1 | SPIRO COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳信立泰药业股份有限公司 | 2024-01-25 | — | — | WO | disclosed |
| CN-116621918-B | Spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116621918-A | Spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-08-22 | — | — | CN | disclosed |