Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12748345 | 0.84 | CSNK2A2 (0.52) | CSNK2A1CSNK2A2CSNK2BADRA2ACLCN2 | |
| SCHEMBL1275907 | 0.79 | ADRA2A (0.50) | CSNK2A1CSNK2A2CSNK2BNOTUMADRA2A | |
| SCHEMBL3613665 | 0.74 | BRPF1 (0.46) | CSNK2A1CSNK2A2CSNK2BNOTUMADRA2A | |
| SCHEMBL17417701 | 0.72 | F7 (0.46) | ADRA2ACLCN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL27034883 | 0.71 | CSNK2A2 (0.41) | CSNK2A1CSNK2A2CSNK2BNOTUMPRKAB2 | |
| SCHEMBL11258062 | 0.71 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BKDM4EHSD17B10 | |
| SCHEMBL12748347 | 0.69 | CYP1A2 (0.57) | CSNK2A1CSNK2A2CSNK2BNOTUMPRKAB2 | |
| SCHEMBL17429455 | 0.69 | PRKAB2 (0.44) | NOTUMPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17417712 | 0.69 | KDM4E (0.45) | NOTUMPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16597462 | 0.68 | CSNK2A2 (0.40) | CSNK2A1CSNK2A2CSNK2BNOTUMPRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990335-A1 | 17 BETA HSD TYPE 5 INHIBITOR | Astellas Pharma Inc. (JP) | 2008-11-12 | — | — | EP | disclosed |