Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446835 | 0.85 | GAA (0.43) | L3MBTL1LMNASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL9877006 | 0.81 | L3MBTL1 (0.47) | L3MBTL1LMNASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL1577289 | 0.74 | TDP1 (0.38) | L3MBTL1LMNASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL3062992 | 0.73 | POLB (0.37) | LMNAALDH1A1CYP3A4KDM4EGAA | |
| SCHEMBL28377189 | 0.73 | L3MBTL1 (0.52) | L3MBTL1LMNASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL10647845 | 0.71 | L3MBTL1 (0.50) | L3MBTL1LMNASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL15674890 | 0.71 | — | — | |
| SCHEMBL10394269 | 0.71 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL2393278 | 0.70 | L3MBTL1 (0.37) | L3MBTL1LMNASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL13026224 | 0.69 | GAA (0.34) | ALDH1A1TDP1CYP3A4HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916660-B1 | Process for the production of sulphonylurea salts | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-16 | — | — | EP | claimed |
| US-6410730-B2 | PREPARING N-PYRIDYLSULFONYL-N'-PYRIMIDINYLUREA SODIUM AND POTASSIUM SALTS BY REACTING A PYRIDYLSULFONAMIDE SALT WITH A PYRIMIDINYL ISOCYANATE, OR A PYRIDYLSULFOCHLORIDE WITH A PYRIMIDINYLUREA SALT | SYNGENTA CROP PROTECTION, INC. | 2002-06-25 | — | — | US | claimed |
| US-20010008938-A1 | Process for preparation of sulfonylurea salts | JAYNJEAN LEVY FAMILY LIMITED PARTNERSHIP | 2001-07-19 | — | — | US | claimed |
| US-6222037-B1 | REACTING 4,6-DIMETHOXYPYRIMIDIN-2-ISOCYANTE WITH 2-SULFONAMIDO-PYRIDINE COMPOUND IN APROTIC SOLVENT TO FORM POTASSIUM OR SODIUM N-PYRIDYLSULFONYL-N'-PYRIMIDINYLUREA COMPOUND | SYNGENTA CROP PROTECTION, INC. | 2001-04-24 | — | — | US | claimed |
| WO-2000052006-A1 | SULFONYLUREA SALTS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-09-08 | — | — | WO | claimed |
| EP-0916660-A2 | Process for the production of sulphonylurea salts | Novartis AG (CH) | 1999-05-19 | — | — | EP | claimed |
| EP-0184385-B1 | N-[(4,6-Dimethoxypyrimidin-2-YL)Aminocarbonyl]-3-trifluoromethylpyridine-2-sulfonamide or salts thereof, herbicidal composition containing the same, and processs for the production of the compound | ISHIHARA SANGYO KAISHA LTD. (JP) | 1990-09-26 | — | — | EP | claimed |
| EP-0184385-A2 | N-[(4,6-Dimethoxypyrimidin-2-YL)Aminocarbonyl]-3-trifluoromethylpyridine-2-sulfonamide or salts thereof, herbicidal composition containing the same, and processs for the production of the compound | ISHIHARA SANGYO KAISHA LTD. (JP) | 1986-06-11 | — | — | EP | claimed |
| JP-11140081-A | — | — | None | — | — | JP | disclosed |
| CN-114933587-A | Preparation method of trifloxysulfuron sodium salt | 江苏省农用激素工程技术研究中心有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-110878084-A | Preparation method of nicosulfuron original drug | 郑州手性药物研究院有限公司 | 2020-03-13 | — | — | CN | disclosed |
| CN-108558830-B | A kind of synthetic method of nicosulfuron raw medicine | 河南恒诚药业有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-108558830-A | A kind of synthetic method of nicosulfuron active compound | 河南恒诚药业有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-106349168-A | Preparation method of foramsulfuron intermediate of sulfonylurea herbicide | 淮安国瑞化工有限公司 | 2017-01-25 | — | — | CN | disclosed |
| US-4935528-A | HERBICIDES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4835282-A | Isothiazoles as intermediates for herbicidal sulfonamides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4822402-A | NONPHYTOTOXIC POSTEMERGENCE WEED CONTROL IN PADDY RICE FIELDS | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0298752-A2 | Mercapto-substituted pyridine compounds and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |
| US-4790869-A | Sulfonamide compounds and salts thereof, herbicidal compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0234352-A1 | Sulfonamide compounds and salts thereof, herbicidal compositions containing them, and process for producing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008938-A1 | Process for preparation of sulfonylurea salts | KCNH1, CLIC1, KCNH3 | L3MBTL1 4362/4885LMNA 1931/4885SMN1; SMN2 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.