SCHEMBL2704263

SCHEMBL2704263

O=C(/C=C(\O)C(F)(F)F)c1ccc(Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
LMNA P02545 3/20 0.59
GAA P10253 2/20 0.59
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
CYP1B1 Q16678 1/20 0.46
POLB P06746 1/20 0.45
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
MAPT P10636 2/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
ALOX12 P18054 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
SRD5A2 P31213 1/20 0.42
MAOB P27338 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2704264 1.00 ALDH1A1 (0.59) ALDH1A1LMNAGAAALOX15TSHR
SCHEMBL2704266 1.00 ALDH1A1 (0.59) ALDH1A1LMNAGAAALOX15TSHR
SCHEMBL15455522 0.98 ALDH1A1 (0.57) ALDH1A1LMNAGAAALOX15TSHR
SCHEMBL15455523 0.98 ALDH1A1 (0.57) ALDH1A1LMNAGAAALOX15TSHR
SCHEMBL15461770 0.84 ALDH1A1 (0.45) ALDH1A1LMNAGAAALOX15TSHR
SCHEMBL22805567 0.83 NR4A2 (0.62) ALDH1A1LMNAGAAPOLBMAPT
SCHEMBL22805565 0.83 NR4A2 (0.62) ALDH1A1LMNAGAAPOLBMAPT
SCHEMBL7361301 0.82 NFE2L2 (0.57) ALDH1A1LMNAGAATSHRCYP1B1
SCHEMBL7361299 0.82 NFE2L2 (0.57) ALDH1A1LMNAGAATSHRCYP1B1
SCHEMBL12900918 0.82 NFE2L2 (0.57) ALDH1A1LMNAGAATSHRCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PROMERUS, LLC (US) 2023-09-19 US disclosed
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PROMERUS, LLC (US) 2023-09-19 US disclosed
US-11746166-B2 UV active derivatives of pd(AcAc)2L catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-09-05 US disclosed
US-11746166-B2 UV active derivatives of pd(AcAc)2L catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-09-05 US disclosed
WO-2023158767-A1 DUAL CATALYST SYSTEM FOR MASS VINYL ADDITION AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 WO disclosed
US-20230265243-A1 DUAL CATALYST SYSTEM FOR MASS VINYL ADDITION AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 US disclosed
US-20230265243-A1 DUAL CATALYST SYSTEM FOR MASS VINYL ADDITION AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 US disclosed
US-20220002453-A1 HINDERED AMINE STABILIZED UV ACTIVE ORGANOPALLADIUM CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2022-01-06 US disclosed
WO-2021262921-A1 HINDERED AMINE STABILIZED UV ACTIVE ORGANOPALLADIUM CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-12-30 WO disclosed
US-20210380733-A1 MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING SOLUBLE PHOTOACID GENERATORS PROMERUS, LLC (US) 2021-12-09 US disclosed
WO-2021138382-A1 UV ACTIVE DERIVATIVES OF PD(ACAC)2 CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-08 WO disclosed
WO-2021138383-A1 UV ACTIVE DERIVATIVES OF Pd(AcAc)2L CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-08 WO disclosed
US-20210198392-A1 UV ACTIVE DERIVATIVES OF Pd(AcAc)2 CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-01 US disclosed
US-20210198393-A1 UV ACTIVE DERIVATIVES OF Pd(AcAc)2L CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-01 US disclosed
US-9359277-B2 Compositions and processes of preparing and using the same PURDUE RESEARCH FOUNDATION (US) 2016-06-07 US disclosed
US-9359277-B2 Compositions and processes of preparing and using the same PURDUE RESEARCH FOUNDATION (US) 2016-06-07 US disclosed
EP-2638089-A1 PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA Bayer Intellectual Property GmbH (DE) 2013-09-18 EP disclosed
WO-2012062658-A1 PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA BAYER MATERIALSCIENCE AG (DE) 2012-05-18 WO disclosed
EP-2450387-A1 Photopolymer formulation for producing holographic media Bayer MaterialScience AG (DE) 2012-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380733-A1 MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING SOLUBLE PHOTOACID GENERATORS PPOX, VCL, PFN1 ALDH1A1 2726/4885LMNA 3936/4885GAA 2571/4885
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PPOX, VCL, PFN1 ALDH1A1 2726/4885LMNA 3936/4885GAA 2571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.