SCHEMBL27043

SCHEMBL27043

CCO/C=C(/CC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.35
SOAT1 P35610 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27044 1.00 FFAR3 (0.35) FFAR3SOAT1HCAR2GRIK1GRIK2
SCHEMBL3555075 1.00 FFAR3 (0.35) FFAR3SOAT1HCAR2GRIK1GRIK2
SCHEMBL984690 0.86 FFAR3 (0.32) FFAR3SOAT1HCAR2
SCHEMBL12801028 0.84 HCAR2 (0.31) HCAR2GRIK1GRIK2
SCHEMBL30965305 0.82 HCAR2 (0.46) SOAT1HCAR2ALDH1A1
SCHEMBL31058784 0.82 HCAR2 (0.46) SOAT1HCAR2ALDH1A1
Benzophenone SCHEMBL10712584 0.82 ELANE (0.47) ALDH1A1
SCHEMBL28845613 0.82 TSHR (0.46) FFAR3HCAR2ALDH1A1KDM4ETSHR
SCHEMBL6308241 0.82 HDAC3 (0.39) FFAR3HCAR2GRIK1GRIK2ALDH1A1
SCHEMBL18044751 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2757133-B1 UV-CURABLE INK FOR DIRECT PLATE MAKING BY INK-JET PRINTING WITH PREPARATION METHOD AND APPLICATION THEREFOR INST CHEMISTRY CAS (CN) 2016-12-28 EP claimed
EP-2807026-A1 MULTILAYER SYSTEMS LANXESS Deutschland GmbH (DE) 2014-12-03 EP claimed
WO-2013110610-A1 MULTILAYER SYSTEMS LANXESS DEUTSCHLAND GMBH (DE) 2013-08-01 WO claimed
EP-2620277-A1 Multi-layer systems LANXESS Deutschland GmbH (DE) 2013-07-31 EP claimed
EP-4545515-A1 BCL-2 INHIBITORS BeiGene Switzerland GmbH (CH) 2025-04-30 EP disclosed
US-12227507-B2 Pharmaceutical compounds PFIZER INC. (US) 2025-02-18 US disclosed
CN-114555604-B Pharmaceutical compounds 辉瑞公司 2024-11-15 CN disclosed
US-20240376104-A1 Bcl-2 Inhibitors BEIGENE LTD. (KY) 2024-11-14 US disclosed
US-12077536-B2 BCL-2 inhibitors BEIGENE, LTD. (KY) 2024-09-03 US disclosed
US-11634425-B2 Pharmaceutical compounds PFIZER INC. (US) 2023-04-25 US disclosed
US-20220402915-A1 BCL-2 INHIBITORS BEONE MEDICINES I GMBH (CH) 2022-12-22 US disclosed
US-20220324873-A1 PHARMACEUTICAL COMPOUNDS PFIZER INC. 2022-10-13 US disclosed
US-20060079707-A1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds PFIZER INC 2006-04-13 US disclosed
WO-2004052313-A2 ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2004-06-24 WO disclosed
EP-1383733-A2 PROCESS FOR THE PREPARATION OF 1,3-SUBSTITUTED INDENES AND ARYL-FUSED AZAPOLYCYCLIC COMPOUNDS Pfizer Products Inc. (US) 2004-01-28 EP disclosed
US-20030060624-A1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic componunds PFIZER INC. 2003-03-27 US disclosed
WO-2002085843-A2 PROCESS FOR THE PREPARATION OF 1,3-SUBSTITUTED INDENES AND ARYL-FUSED AZAPOLYCYCLIC COMPOUNDS PFIZER PRODUCTS INC. (US) 2002-10-31 WO disclosed
US-6395920-B1 OBTAINING 2-SUBSTITUTED AND 2,2- DISUBSTITUTED ACETALS OF MALONDIALDEHYDE FROM ORTHO FORMATES AND SUBSTITUTED VINYL ETHERS IN THE PRESENCE OF AN ACIDIC CATALYST CREANOVA, INC. 2002-05-28 US disclosed
US-20020040166-A1 PROCESS FOR PREPARING SUBSTITUTED ACETALS OF MALONDIALDEHYDE CREANOVA, INC. 2002-04-04 US disclosed
US-5177116-A Polysiloxane BASF CORPORATION (US) 1993-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402915-A1 BCL-2 INHIBITORS BCL2, BCL2L1, BCL2L2 FFAR3 2823/4885SOAT1 2303/4885HCAR2 2165/4885
US-12227507-B2 Pharmaceutical compounds CHRNA6, GABRA6, CHRNA7 FFAR3 684/4885SOAT1 1440/4885HCAR2 378/4885
US-12077536-B2 BCL-2 inhibitors BCL2, BCL2L1, BCL2L2 FFAR3 2823/4885SOAT1 2303/4885HCAR2 2165/4885
US-20060079707-A1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds CYP1B1, AZI2, CYP1A1 FFAR3 3018/4885SOAT1 3837/4885HCAR2 2099/4885
US-20240376104-A1 Bcl-2 Inhibitors BCL2, BCL2L1, BCL2L2 FFAR3 2823/4885SOAT1 2303/4885HCAR2 2165/4885
US-11634425-B2 Pharmaceutical compounds GABRA6, CHRNA6, CNR1 FFAR3 953/4885SOAT1 1663/4885HCAR2 422/4885
US-20020040166-A1 PROCESS FOR PREPARING SUBSTITUTED ACETALS OF MALONDIALDEHYDE AOX1, GPX4, NOX4 FFAR3 1717/4885SOAT1 1178/4885HCAR2 3037/4885
US-20030060624-A1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic componunds INTS6, CYP1B1, CYP1A2 FFAR3 3924/4885SOAT1 2915/4885HCAR2 2447/4885
US-20220324873-A1 PHARMACEUTICAL COMPOUNDS GABRA6, CNR1, CHRNA6 FFAR3 903/4885SOAT1 1896/4885HCAR2 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.