Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21319396 | 0.79 | CYP2D6 (0.48) | KDM1ACHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL15305673 | 0.77 | — | — | |
| SCHEMBL18779843 | 0.77 | MAPT (0.37) | — | |
| SCHEMBL27056130 | 0.77 | POLB (0.38) | KDM1ABCHEHRH3CHRM2CHRM4 | |
| SCHEMBL15304786 | 0.77 | — | — | |
| SCHEMBL27056167 | 0.76 | ADRA2A (0.43) | HRH3CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL19759877 | 0.76 | ALDH1A1 (0.33) | KDM1A | |
| SCHEMBL15362393 | 0.74 | KDM1A (0.46) | KDM1AFPR2HRH3CHRM2CHRM4 | |
| SCHEMBL15362392 | 0.73 | DRD2 (0.45) | KDM1AHRH3CHRM2CHRM4HTR1A | |
| SCHEMBL15362396 | 0.72 | LMNA (0.45) | KDM1AFPR2HRH3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473254-B1 | PHENOTHIAZINE DERIVATIVES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2024-01-24 | — | — | EP | disclosed |