SCHEMBL270591

SCHEMBL270591

COC(=O)c1nccnc1NS(=O)(=O)CC(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.33
ATR Q13535 1/20 0.33
CA12 O43570 3/20 0.33
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
ACLY P53396 1/20 0.32
CCNB2 O95067 1/20 0.32
CCNE2 O96020 1/20 0.32
CDK1 P06493 1/20 0.32
CDK4 P11802 1/20 0.32
CCNB1 P14635 1/20 0.32
CCND1 P24385 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
CCNB3 Q8WWL7 1/20 0.32
SCD O00767 1/20 0.31
HPGD P15428 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271449 0.88 L3MBTL1 (0.37) L3MBTL1CA12CA2CA1CA9
SCHEMBL360646 0.74 L3MBTL1 (0.39) L3MBTL1ATRCCNB2CCNE2CDK1
SCHEMBL272019 0.71 PTGDR2 (0.37) L3MBTL1ACLYGAAMEN1KMT2A
SCHEMBL269856 0.70 KEAP1 (0.32)
SCHEMBL271872 0.70 SCD (0.42) L3MBTL1SCDHPGDGAANPSR1
SCHEMBL271264 0.70 L3MBTL1 (0.37) L3MBTL1CA12CA2CA1CA9
SCHEMBL271411 0.70 GRM4 (0.43) SCDGAATDP1ALDH1A1KMT2A
SCHEMBL271318 0.69 ALDH1A1 (0.37) L3MBTL1ACLYSCDHPGDPOLB
SCHEMBL271252 0.69 CCR4 (0.38) L3MBTL1ACLYSCDHPGDGAA
SCHEMBL270666 0.69 ABL1 (0.38) L3MBTL1CA12CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220056-B1 HERBICIDAL COMPOUNDS SYNGENTA LTD (GB) 2015-09-30 EP disclosed
US-8133849-B2 Herbicidal compounds SYNGENTA LIMITED (GB) 2012-03-13 US disclosed
US-20100323889-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323889-A1 HERBICIDAL COMPOUNDS CBR3, DDT, CBR1 L3MBTL1 2902/4885ATR 2791/4885CA12 2376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.