SCHEMBL270613

SCHEMBL270613

COC(=O)c1nccnc1NS(=O)(=O)C(CC(F)F)C(=O)OC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
ACLY P53396 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12296252 0.72 SCD (0.44) SCDL3MBTL1
SCHEMBL271449 0.70 L3MBTL1 (0.37) SCDL3MBTL1ACLYGAA
SCHEMBL15360305 0.66 NPSR1 (0.46) SCDL3MBTL1
SCHEMBL270591 0.65 L3MBTL1 (0.33) SCDL3MBTL1ACLYGAA
SCHEMBL71518 0.65 NPSR1 (0.59) L3MBTL1GAA
SCHEMBL272019 0.64 PTGDR2 (0.37) L3MBTL1ACLYGAA
SCHEMBL271334 0.64 ACLY (0.38) SCDL3MBTL1ACLYGAA
SCHEMBL271411 0.64 GRM4 (0.43) SCDGAA
SCHEMBL271872 0.63 SCD (0.42) SCDL3MBTL1GAA
SCHEMBL271264 0.63 L3MBTL1 (0.37) SCDL3MBTL1ACLYGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220056-B1 HERBICIDAL COMPOUNDS SYNGENTA LTD (GB) 2015-09-30 EP disclosed
US-8133849-B2 Herbicidal compounds SYNGENTA LIMITED (GB) 2012-03-13 US disclosed
US-20100323889-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-12-23 US disclosed
EP-2220056-A1 HERBICIDAL COMPOUNDS Syngenta Limited (GB) 2010-08-25 EP disclosed
WO-2009063180-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323889-A1 HERBICIDAL COMPOUNDS CBR3, DDT, CBR1 SCD 3715/4885L3MBTL1 2902/4885ACLY 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.