Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23103993 | 0.76 | CCR1 (0.33) | — | |
| SCHEMBL23108649 | 0.72 | IDO1 (0.32) | ALOX5AP | |
| SCHEMBL19381987 | 0.70 | TRPA1 (0.38) | TAAR1ALOX5APFEN1 | |
| SCHEMBL23114543 | 0.68 | MAOA (0.41) | — | |
| SCHEMBL27066490 | 0.67 | KCNH2 (0.37) | ALOX5APFEN1 | |
| SCHEMBL7261883 | 0.65 | RPS6KA3 (0.51) | — | |
| SCHEMBL21467014 | 0.63 | ALDH1A1 (0.42) | — | |
| SCHEMBL23103358 | 0.61 | ALOX5AP (0.35) | ALOX5APFEN1 | |
| SCHEMBL23133623 | 0.61 | PIM1 (0.33) | ALOX5APFEN1 | |
| SCHEMBL18019530 | 0.59 | CCR1 (0.52) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | TAAR1 4620/4885ALOX5AP 3256/4885FEN1 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.