SCHEMBL24728587

SCHEMBL24728587

c1ccc2c(c1)oc1c2ccc2[nH]c3ccc4c5ccccc5oc4c3c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.53
ZAP70 P43403 1/20 0.53
SYK P43405 1/20 0.53
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43
GABRG3 Q99928 1/20 0.43
GABRQ Q9UN88 1/20 0.43
PGR P06401 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655467 0.91 GABRA1 (0.51) JAK2ZAP70SYKGABRPGABRD
SCHEMBL29819648 0.91 GABRA1 (0.51) JAK2ZAP70SYKGABRPGABRD
SCHEMBL31846 0.91 GABRA1 (0.51) JAK2ZAP70SYKGABRPGABRD
SCHEMBL14951860 0.90 L3MBTL1 (0.47) JAK2ZAP70SYKGABRPGABRD
SCHEMBL29655439 0.87 JAK2 (0.45) JAK2ZAP70SYKGABRPGABRD
SCHEMBL28643524 0.87 JAK2 (0.45) JAK2ZAP70SYKGABRPGABRD
SCHEMBL14951209 0.87 GABRP (0.47) JAK2ZAP70SYKGABRPGABRD
SCHEMBL18926345 0.86 GABRA1 (0.50) JAK2ZAP70SYKGABRPGABRD
SCHEMBL23268712 0.85 JAK2 (0.49) JAK2ZAP70SYKGABRPGABRD
SCHEMBL19784917 0.84 JAK2 (0.45) JAK2ZAP70SYKGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117940431-A Compound, light-emitting material, and light-emitting element 九州有机光材股份有限公司 2024-04-26 CN disclosed
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 US disclosed
US-20230210000-A1 COMPOUND, LIGHT EMITTING MATERIAL, AND LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2023-06-29 US disclosed
EP-4190791-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT Kyulux, Inc. (JP) 2023-06-07 EP disclosed
EP-4102588-A1 HOST MATERIAL, COMPOSITION, AND ORGANIC ELECTROLUMINESCENT ELEMENT Kyulux, Inc. (JP) 2022-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CCNE2, CRY2 JAK2 2128/4885ZAP70 4362/4885SYK 4364/4885
US-20230210000-A1 COMPOUND, LIGHT EMITTING MATERIAL, AND LIGHT EMITTING DEVICE DRD1, DRD2, DRD3 JAK2 2622/4885ZAP70 4759/4885SYK 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.