Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030672 | 0.84 | KDM1A (0.59) | KDM1AEGFRALDH1A1TSHRMAPT | |
| SCHEMBL28557487 | 0.78 | KDM1A (0.63) | KDM1AEGFRALDH1A1TSHRMAPT | |
| SCHEMBL27085709 | 0.74 | NEK2 (0.45) | — | |
| SCHEMBL8842433 | 0.74 | RAPGEF4 (0.46) | EGFRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31652360 | 0.73 | MEN1 (0.54) | EGFRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3174911 | 0.73 | HSD17B10 (0.33) | ALDH1A1TSHRKMT2AALOX15MAPK1 | |
| SCHEMBL10571080 | 0.72 | KDM1A (0.53) | KDM1AEGFRALDH1A1TSHRMAPT | |
| SCHEMBL9649012 | 0.72 | ALDH1A1 (0.53) | KDM1AEGFRALDH1A1TSHRMAPT | |
| SCHEMBL3958554 | 0.72 | HSD17B10 (0.57) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL1268756 | 0.70 | ALDH1A1 (0.50) | KDM1AEGFRALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897883-B1 | Pyrrolo[3,2-c][1,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2024-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897883-B1 | Pyrrolo[3,2-c][1,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | CSNK2A2, CSNK2A1, CSNK2A3 | KDM1A 2963/4885EGFR 942/4885ALDH1A1 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.