Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090467 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27090463 | 0.79 | LMNA (0.45) | HPGDALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL27090511 | 0.78 | LMNA (0.42) | SMN1; SMN2HPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27090461 | 0.78 | LMNA (0.42) | SMN1; SMN2HPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27090502 | 0.75 | LMNA (0.50) | HPGDALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL27090489 | 0.75 | RAB9A (0.46) | SMN1; SMN2HPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27090471 | 0.71 | LMNA (0.42) | SMN1; SMN2HPGDALDH1A1CYP1A2LMNA | |
| SCHEMBL18880336 | 0.71 | PTPN1 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2C19PTPN1 | |
| SCHEMBL23634786 | 0.66 | LMNA (0.54) | HPGDALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL18482099 | 0.65 | LMNA (0.50) | HPGDALDH1A1CYP1A2LMNACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051897-A1 | SYNTHESIS OF COMPLEX 15N-LABELED MOLECULES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2024-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051897-A1 | SYNTHESIS OF COMPLEX 15N-LABELED MOLECULES | NCLN, NCL, NDUFV3 | SMN1; SMN2 1816/4885HPGD 584/4885ALDH1A1 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.