Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.35 |
| ▸ | CDK9 | P50750 | 7/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24493583 | 0.79 | HRH3 (0.40) | APAF1CASP3SENP8SENP7SENP6 | |
| SCHEMBL24493582 | 0.78 | HRH3 (0.40) | APAF1CASP3SENP8SENP7SENP6 | |
| SCHEMBL27095822 | 0.76 | CCNT1 (0.42) | ENPP2CCNT1CDK9ACHE | |
| SCHEMBL429671 | 0.74 | LOXL2 (0.51) | HRH3 | |
| SCHEMBL30578250 | 0.74 | LOXL2 (0.51) | HRH3 | |
| SCHEMBL27095873 | 0.74 | GSK3B (0.40) | APAF1CASP3SENP8SENP7SENP6 | |
| SCHEMBL27095987 | 0.73 | CCNT1 (0.42) | APAF1CASP3SENP8SENP7SENP6 | |
| SCHEMBL27096082 | 0.73 | APAF1 (0.40) | APAF1CASP3SENP8SENP7SENP6 | |
| SCHEMBL24493350 | 0.72 | APAF1 (0.41) | APAF1CASP3SENP8SENP7SENP6 | |
| SCHEMBL24493315 | 0.72 | MRGPRX1 (0.47) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059691-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2024-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059691-A1 | ENZYME INHIBITORS | SERPINB1, XDH, ACE | APAF1 919/4885CASP3 2487/4885SENP8 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.