Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26739795 | 0.75 | ASIC3 (0.53) | TSHRALDH1A1KDM4E | |
| SCHEMBL3230717 | 0.71 | PRMT6 (0.68) | CYP1A2CYP3A4CYP2C19CYP2D6CLK4 | |
| SCHEMBL16285497 | 0.70 | PLK1 (0.50) | CYP1A2CYP3A4ALDH1A1PRMT6MAPT | |
| SCHEMBL2480308 | 0.70 | FDPS (0.53) | AAK1MAPT | |
| SCHEMBL28116354 | 0.70 | ASIC3 (0.53) | — | |
| SCHEMBL12408985 | 0.70 | ASIC3 (0.53) | — | |
| SCHEMBL24137789 | 0.69 | NOS2 (0.51) | NOS2AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL25633157 | 0.69 | ASIC3 (0.52) | — | |
| SCHEMBL14677313 | 0.69 | PRMT6 (0.64) | CLK4PRMT6 | |
| SCHEMBL2521580 | 0.68 | CCR1 (0.48) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912682-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912682-B2 | Isoindolinone compounds | CYP4F2, AOC2, AOC3 | NOS2 1908/4885AAK1 4560/4885CYP1A2 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.