Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064698 | 0.88 | SLC6A9 (0.52) | SLC6A9KCNH2ALDH1A1MEN1HPGD | |
| SCHEMBL2825364 | 0.86 | SLC6A9 (0.51) | SLC6A9KCNH2ALDH1A1MEN1HPGD | |
| SCHEMBL1814036 | 0.76 | LMNA (0.48) | SLC6A9KCNH2CYP2C9PTGDR2CYP2D6 | |
| SCHEMBL19604253 | 0.76 | ABCB1 (0.50) | ALDH1A1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL3882695 | 0.74 | LMNA (0.46) | SLC6A9KCNH2ALDH1A1MEN1HPGD | |
| SCHEMBL4422116 | 0.74 | EPAS1 (0.43) | SLC6A9KCNH2ALDH1A1MEN1HPGD | |
| SCHEMBL2825627 | 0.74 | LMNA (0.51) | SLC6A9KCNH2CYP2C9PTGDR2CYP2D6 | |
| SCHEMBL28064700 | 0.74 | PTGS2 (0.44) | SLC6A9KCNH2ALDH1A1MEN1HPGD | |
| SCHEMBL3873094 | 0.74 | SLC6A9 (0.56) | SLC6A9KCNH2PTGDR2PTGS2LMNA | |
| SCHEMBL5183828 | 0.74 | LMNA (0.48) | SLC6A9KCNH2CYP2C9PTGDR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024042043-A1 | A SCALABLE PROCESS FOR THE PREPARATION OF A GLYT-1 INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |