Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12659328 | 0.89 | NPC1 (0.45) | CA5ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28024789 | 0.83 | AKR1C3 (0.43) | CA5ANPC1RAB9ASMN1; SMN2TTR | |
| SCHEMBL27260102 | 0.82 | CA5A (0.50) | CA5ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL1071876 | 0.80 | TTR (0.62) | CA5ASMN1; SMN2ACP1LMNATTR | |
| SCHEMBL1191399 | 0.80 | TTR (0.62) | CA5ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28024881 | 0.80 | CA5A (0.48) | CA5ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31248956 | 0.79 | CYP1A2 (0.47) | SMN1; SMN2LMNAALDH1A1HPGDGAA | |
| SCHEMBL24129342 | 0.78 | ACP1 (0.39) | NPC1RAB9ASMN1; SMN2ACP1TTR | |
| SCHEMBL1003817 | 0.78 | TSHR (0.53) | SMN1; SMN2ACP1LMNATTRHSD17B10 | |
| SCHEMBL5104318 | 0.78 | GSK3B (0.57) | CA5ANPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067659-A1 | METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND | JW PHARMACEUTICAL CORPORATION (KR) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067659-A1 | METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND | REN, NOD1, NLRP3 | CA5A 194/4885NPC1 504/4885RAB9A 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.