Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CCKAR | P32238 | 3/20 | 0.47 |
| ▸ | CCKBR | P32239 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27109780 | 0.95 | CHRNB2 (0.52) | PSMB5FAAHCCKARCCKBRCHRNB2 | |
| SCHEMBL27377107 | 0.89 | CCKAR (0.47) | PSMB5FAAHCCKARCCKBRCHRNB2 | |
| SCHEMBL27378254 | 0.86 | PSMB5 (0.48) | PSMB5CCKARCCKBRCHRNB2CHRNB4 | |
| SCHEMBL25497019 | 0.85 | FAAH (0.60) | PSMB5FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25496878 | 0.84 | FAAH (0.53) | PSMB5FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23718677 | 0.84 | FAAH (0.52) | PSMB5FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25148144 | 0.84 | FAAH (0.56) | PSMB5FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24982484 | 0.82 | FAAH (0.50) | PSMB5FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27433914 | 0.82 | PSMB5 (0.56) | PSMB5FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL26154311 | 0.82 | FAAH (0.52) | PSMB5FAAHPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044554-A1 | VHH ANTIBODY CONJUGATES WITH HETEROARYL CHELATORS | Abdera Therapeutics Inc. (US) | 2024-02-29 | — | — | WO | disclosed |