Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271924 | 0.90 | POLB (0.32) | POLBMCOLN3ACLYALDH1A1 | |
| SCHEMBL271967 | 0.89 | P2RX7 (0.35) | POLBMCOLN3ACLYALDH1A1TSHR | |
| SCHEMBL271332 | 0.89 | ATM (0.38) | POLBMCOLN3ACLYALDH1A1MAPT | |
| SCHEMBL271417 | 0.82 | ALDH1A1 (0.39) | POLBMCOLN3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL271519 | 0.82 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL271319 | 0.80 | POLB (0.35) | POLBMCOLN3ACLYALDH1A1TSHR | |
| SCHEMBL271950 | 0.80 | ACLY (0.35) | POLBMCOLN3ACLYALDH1A1TSHR | |
| SCHEMBL271665 | 0.79 | P2RX7 (0.33) | POLBMCOLN3ACLYALDH1A1 | |
| SCHEMBL271957 | 0.79 | P2RX7 (0.37) | POLBMCOLN3ACLYL3MBTL1MAPT | |
| SCHEMBL271718 | 0.79 | RORC (0.33) | POLBMCOLN3ACLYALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | POLB 3661/4885MCOLN3 3768/4885ACLY 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.