Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271319 | 0.92 | POLB (0.35) | P2RX7POLBMCOLN3ACLYALDH1A1 | |
| SCHEMBL271718 | 0.90 | RORC (0.33) | P2RX7POLBMCOLN3ACLYALDH1A1 | |
| SCHEMBL271924 | 0.90 | POLB (0.32) | POLBMCOLN3ACLYALDH1A1KEAP1 | |
| SCHEMBL271967 | 0.90 | P2RX7 (0.35) | P2RX7POLBMCOLN3ACLYALDH1A1 | |
| SCHEMBL271422 | 0.85 | TSHR (0.32) | POLBMCOLN3ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL271937 | 0.84 | POLB (0.37) | POLBMCOLN3ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL271791 | 0.81 | P2RX7 (0.35) | P2RX7POLBMCOLN3ACLYKEAP1 | |
| SCHEMBL271761 | 0.81 | GLS (0.33) | POLBMCOLN3ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL271420 | 0.80 | P2RX7 (0.34) | P2RX7POLB | |
| SCHEMBL271663 | 0.80 | KEAP1 (0.34) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | P2RX7 1479/4885POLB 3661/4885MCOLN3 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.