SCHEMBL27129458

SCHEMBL27129458

COc1ccnc(-n2ccc(C)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CCR1 P32246 1/20 0.46
CCR5 P51681 1/20 0.46
CCR8 P51685 1/20 0.46
NOS3 P29474 2/20 0.43
NOS1 P29475 2/20 0.43
NOS2 P35228 2/20 0.43
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.41
DYRK1A Q13627 2/20 0.39
PLAU P00749 1/20 0.37
KDM5A P29375 3/20 0.37
KDM4C Q9H3R0 3/20 0.37
KDM5B Q9UGL1 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11983495 0.80 RAB9A (0.52) MAPTRAB9ASMN1; SMN2NPC1ATM
SCHEMBL27130379 0.77 CCR1 (0.46) MAPTSMN1; SMN2L3MBTL1CCR1CCR5
SCHEMBL15935018 0.77 MAPT (0.54) MAPTRAB9ASMN1; SMN2NPC1ATM
SCHEMBL24920394 0.75 NPC1 (0.49) MAPTRAB9ASMN1; SMN2NPC1CCR1
SCHEMBL15935019 0.74 SMN1; SMN2 (0.46) MAPTRAB9ASMN1; SMN2NPC1ATM
SCHEMBL24921166 0.74 CCR1 (0.46) MAPTSMN1; SMN2CCR1CCR5CCR8
SCHEMBL24378467 0.73 NOTUM (0.57) MAPTRAB9ASMN1; SMN2NPC1ATM
SCHEMBL15779263 0.73 GRM5 (0.46) MAPTRAB9ASMN1; SMN2NPC1ATM
SCHEMBL16547542 0.73 ALDH1A1 (0.50) MAPTRAB9ASMN1; SMN2NPC1L3MBTL1
SCHEMBL22894874 0.73 MAPT (0.45) MAPTRAB9ASMN1; SMN2NPC1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376513-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-11-14 US disclosed
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
CN-117242084-A Electrochemical biosensor comprising transition metal complex or redox polymer or sensing membrane for electrochemical biosensor 爱-森新株式会社 2023-12-15 CN disclosed
WO-2022225313-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER 주식회사 아이센스 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376513-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER OXA1L, PDK1, SLC2A3 MAPT 2304/4885RAB9A 3858/4885SMN1; SMN2 4611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.