Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282811 | 0.93 | CES2 (0.54) | CES2CES1CA1CA2GSK3B | |
| Ethylene SCHEMBL10490014 | 0.78 | LMNA (0.67) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL615632 | 0.78 | CES2 (0.62) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL3842531 | 0.77 | LMNA (0.73) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL557285 | 0.77 | CES2 (1.00) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL9126141 | 0.77 | LMNA (0.73) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL132367 | 0.77 | LMNA (0.73) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL1442016 | 0.77 | MAPT (0.44) | CA1CA2GSK3BLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL5283915 | 0.76 | CES2 (0.59) | CES2CES1CA1CA2GSK3B | |
| Hydrochloric Acid SCHEMBL4372828 | 0.76 | CES2 (0.59) | CES2CES1CA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1951 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239647-A | Benzimidazole alkyl bromide-timosaponin derivative and preparation method and application thereof | 云南大学 | 2023-06-09 | — | — | CN | claimed |
| CN-110078717-B | Bis-benzofuran-benzimidazole salt compound with anti-tumor activity and preparation method thereof | 红河学院 | 2022-04-26 | — | — | CN | claimed |
| EP-2955575-B1 | RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, AND POLYPHENOL DERIVATIVE USED IN SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-07-29 | — | — | EP | claimed |
| CN-108299401-B | 3-benzyl substituted coumarin-imidazole salt compound and preparation method thereof | 红河学院 | 2020-06-30 | — | — | CN | claimed |
| US-10377734-B2 | Resist composition, method for forming resist pattern, polyphenol derivative for use in the composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-08-13 | — | — | US | claimed |
| US-9897913-B2 | Radiation-sensitive composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2018-02-20 | — | — | US | claimed |
| US-9714560-B2 | Protected scale inhibitors and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-25 | — | — | US | claimed |
| EP-2132201-B1 | NOVEL 2-HETEROARYL SUBSTITUTED BENZOTHIOPHENES AND BENZOFURANES | ASTRAZENECA AB (SE) | 2016-11-16 | — | — | EP | claimed |
| US-9493469-B2 | Piperidine inhibitors of Janus kinase 3 | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | claimed |
| US-8957215-B2 | Heteroaryl substituted benzothiazoles | NAVIDEA BIOPHARMACEUTICALS, INC. (US) | 2015-02-17 | — | — | US | claimed |
| US-4053286-A | ACYLATION | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | claimed |
| US-4051132-A | Process for epimerizing beta-lactam antibiotic compounds by means of an acid quench | MERCK & CO., INC. (US) | 1977-09-27 | — | — | US | claimed |
| US-4031082-A | Process for preparing 3-acycloxymethyl-2-cephem compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | claimed |
| US-4029651-A | ESTERIFICATION | ELI LILLY AND COMPANY (US) | 1977-06-14 | — | — | US | claimed |
| US-4016155-A | Process for preparing cephalosporin derivatives | SANKYO COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | claimed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | claimed |
| US-3997533-A | Process for the preparation of 7-acylamino-desacetoxycephalosporanic derivatives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |
| US-3978078-A | Process for the preparation of ampicillin | RHONE-POULENC S.A. (FR) | 1976-08-31 | — | — | US | claimed |
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | claimed |
| US-3953437-A | Process of preparing cephalosporanic acid ester derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377734-B2 | Resist composition, method for forming resist pattern, polyphenol derivative for use in the composition | HEATR1, HSP90AB1, HSP90AA1 | CES2 3244/4885CES1 3870/4885CA1 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.