Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 1.00 |
| ▸ | CES1 | P23141 | 6/20 | 1.00 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525907 | 0.92 | CES2 (0.84) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL649996 | 0.89 | CES2 (0.80) | CES2CES1CA1CA2HPGD | |
| SCHEMBL29825996 | 0.89 | CES2 (0.80) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL5388314 | 0.87 | CES2 (0.76) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL12204728 | 0.87 | CES2 (0.76) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL4196624 | 0.87 | CES2 (0.76) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL3500800 | 0.86 | CES2 (0.75) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL11795251 | 0.85 | CES2 (0.73) | CES2CES1CA1CA2HTT | |
| SCHEMBL4187858 | 0.85 | CES2 (0.73) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL8387086 | 0.85 | LMNA (0.76) | CES2CES1CA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217500-B | Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof | 黑龙江大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119613746-A | Directably modified hexabenzo-metal organic framework, and preparation method and application thereof | 南开大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119552352-A | Triphenylamine polyamide containing quinoxaline structure, and preparation method and application thereof | 黑龙江大学 | 2025-03-04 | — | — | CN | claimed |
| US-20250033082-A1 | METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS | ADAMA MAKHTESHIM LTD. (IL) | 2025-01-30 | — | — | US | claimed |
| US-12180181-B1 | 4-[4,5-bis(4-bromophenyl)-1-hexyl-1H-imidazol-2-yl]isoquinolin-3-ol as an antimicrobial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | claimed |
| US-12180166-B1 | 6-(4,5-bis(4-bromophenyl)-2-(4-methoxyphenyl)-1H-imidazol-1-yl)hexanoic acid as an antimicrobial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | claimed |
| US-12172967-B1 | 3-(4,5-bis(4-bromophenyl)-2-(4-chlorophenyl)-1H-imidazol-1-yl)propanoic acid as an antimicrobial compound | King Faisal University (SA) | 2024-12-24 | — | — | US | claimed |
| US-12162839-B1 | 4,5-bis(4-bromophenyl)-2-(4-bromophenyl)-1-hexyl-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-12-10 | — | — | US | claimed |
| CN-117417248-B | Molecular-level monolayer hydrophilic graphene quantum dot and preparation method thereof | 武汉科技大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118750912-A | Delayed coking defoaming agent and preparation method thereof | 江苏创新石化有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-113817140-A | Dendritic polymer and preparation method thereof | 中电科技集团重庆声光电有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-112939975-A | Thermal activation delayed fluorescent material, preparation method and application | 天津大学 | 2021-06-11 | — | — | CN | claimed |
| CN-112194630-A | Preparation and application of organic hole transport material with imidazole derivative as core | 南京林业大学 | 2021-01-08 | — | — | CN | claimed |
| CN-110845503-A | Preparation and application of arylamine substituted benzodiindole organic hole transport material | 南京林业大学 | 2020-02-28 | — | — | CN | claimed |
| CN-110343100-A | A kind of phenothiazines is total to sensitizer and its preparation method and application | 江苏理工学院 | 2019-10-18 | — | — | CN | claimed |
| US-7973034-B2 | Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2011-07-05 | — | — | US | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-0043480-B1 | PROCESS FOR FORMING METALLIC IMAGES | Hitachi, Ltd. (JP) | 1985-04-03 | — | — | EP | claimed |
| US-4347304-A | PHOTOSENSITIZATION WITH DISILANES OR ORGANIC COMPOUNDS HAVING COUPLED GERMANIUM OR TIN MOLECULES; PHOTORESISTS; POSITIVES; PLATING | HITACHI, LTD. (JP) | 1982-08-31 | — | — | US | claimed |
| EP-0043480-A2 | Process for forming metallic images | Hitachi, Ltd. (JP) | 1982-01-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12180181-B1 | 4-[4,5-bis(4-bromophenyl)-1-hexyl-1H-imidazol-2-yl]isoquinolin-3-ol as an antimicrobial compound | IRF3, IFNG, TLR4 | CES2 4013/4885CES1 4139/4885CA1 4871/4885 |
| US-12172967-B1 | 3-(4,5-bis(4-bromophenyl)-2-(4-chlorophenyl)-1H-imidazol-1-yl)propanoic acid as an antimicrobial compound | DPP4, DPP3, EBP | CES2 3479/4885CES1 1745/4885CA1 4517/4885 |
| US-12162839-B1 | 4,5-bis(4-bromophenyl)-2-(4-bromophenyl)-1-hexyl-1H-imidazole as an antimicrobial compound | BRD4, IL4, CASP4 | CES2 2907/4885CES1 4001/4885CA1 4851/4885 |
| US-12180166-B1 | 6-(4,5-bis(4-bromophenyl)-2-(4-methoxyphenyl)-1H-imidazol-1-yl)hexanoic acid as an antimicrobial compound | HK1, GCK, HK2 | CES2 3683/4885CES1 2498/4885CA1 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.