Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.33 |
| ▸ | PTGIR | P43119 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214727 | 0.79 | HCAR2 (0.42) | KDM5AKDM4AHCAR2KDM4C | |
| SCHEMBL28052660 | 0.74 | LMNA (0.37) | CNR2PTGIRCHRM3PTGDR | |
| SCHEMBL12985873 | 0.73 | HCAR2 (0.45) | KDM5AKDM4AHCAR2KDM4C | |
| SCHEMBL19815488 | 0.72 | ACMSD (0.42) | KDM5AKDM4AHCAR2 | |
| SCHEMBL21616804 | 0.69 | PRKAB2 (0.39) | KDM5AKDM4AHCAR2KDM4C | |
| SCHEMBL19335252 | 0.67 | CNR2 (0.34) | CNR2CNR1CHRM3 | |
| SCHEMBL28705014 | 0.67 | SLC1A3 (0.33) | CNR2CHRM3 | |
| SCHEMBL3068424 | 0.66 | HDAC1 (0.33) | — | |
| SCHEMBL10150825 | 0.66 | LMNA (0.50) | — | |
| SCHEMBL25123646 | 0.66 | ACHE (0.51) | PTGIRCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |