Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31521744 | 0.82 | MKNK1 (0.47) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL24793478 | 0.82 | ADRB2 (0.56) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27174522 | 0.82 | MKNK1 (0.47) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30211282 | 0.79 | SLC2A1 (0.48) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL411041 | 0.79 | SLC2A1 (0.48) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30007391 | 0.79 | MAPK14 (0.53) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30211300 | 0.79 | MAPK14 (0.53) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27174505 | 0.79 | CYP2A6 (0.51) | TRPV1AKT1 | |
| SCHEMBL2639667 | 0.77 | FEN1 (0.43) | TRPV1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29604199 | 0.77 | FEN1 (0.43) | TRPV1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547336-A1 | USP1 INHIBITORS AND USES THEREOF | Zentaur Therapeutics USA Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119836421-A | USP1 inhibitors and uses thereof | 森韬医药美国公司 | 2025-04-15 | — | — | CN | disclosed |
| US-20240092779-A1 | USP1 INHIBITORS AND USES THEREOF | ZENTAUR THERAPEUTICS USA INC. | 2024-03-21 | — | — | US | disclosed |
| WO-2024006879-A1 | USP1 INHIBITORS AND USES THEREOF | ZENTAUR THERAPEUTICS USA INC. (US) | 2024-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092779-A1 | USP1 INHIBITORS AND USES THEREOF | USP1, USP28, USP2 | TRPV1 4823/4885GABRG2 3026/4885GABRB3 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.