SCHEMBL2717547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266633	0.92	EPHX2 (0.40)	EPHX2PHGDHADORA3NR1H4SCN9A
	SCHEMBL2713055	0.90	ROCK2 (0.48)	PHGDHSCN9AROCK2ROCK1
	SCHEMBL2716641	0.88	ROCK2 (0.49)	EPHX2ADORA3MEN1GAAKMT2A
	SCHEMBL2716773	0.85	EPHX2 (0.48)	EPHX2NR1H4CYP3A4
	SCHEMBL2716175	0.83	ADORA3 (0.42)	EPHX2ADORA3NR1H4PPARGRIPK1
	SCHEMBL2715424	0.83	KMT2A (0.58)	MMP13MEN1PLA2G1BCYP1A2CYP3A4
	SCHEMBL2715367	0.83	RIPK1 (0.44)	EPHX2SCN9APPARGCYP3A4RIPK1
	SCHEMBL18266463	0.82	PPARG (0.41)	EPHX2ADORA3NR1H4SCN9APPARG
	SCHEMBL2715751	0.82	MLYCD (0.51)	ADORA3SCN9AMEN1PLA2G1BCYP1A2
	SCHEMBL18266769	0.82	SMN1; SMN2 (0.42)	EPHX2ADORA3MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.