SCHEMBL2716641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266769	0.92	SMN1; SMN2 (0.42)	ROCK2ROCK1EPHX2ADORA3SMN1; SMN2
	SCHEMBL2717547	0.88	EPHX2 (0.46)	ROCK2ROCK1EPHX2ADORA3MEN1
	SCHEMBL2718582	0.88	LMNA (0.46)	ADORA3SMN1; SMN2ALDH1A1LMNAMAPK1
	SCHEMBL2713699	0.87	ALDH1A1 (0.47)	SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
	SCHEMBL2713055	0.86	ROCK2 (0.48)	ROCK2ROCK1
	SCHEMBL2716175	0.84	ADORA3 (0.42)	ROCK2EPHX2ADORA3
	SCHEMBL2715367	0.83	RIPK1 (0.44)	EPHX2
	SCHEMBL18266599	0.83	LMNA (0.44)	ADORA3SMN1; SMN2ALDH1A1MEN1KMT2A
	SCHEMBL18266463	0.83	PPARG (0.41)	EPHX2ADORA3
	SCHEMBL2717997	0.82	RIPK1 (0.43)	ROCK2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.