SCHEMBL4889487

SCHEMBL4889487

CCCC1(CC)C(=O)NC(=O)NC1=O

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.73
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
GABRB3 P28472 1/20 0.44
OPRD1 P41143 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
MMP9 P14780 7/20 0.43
MMP2 P08253 6/20 0.43
MMP8 P22894 4/20 0.43
MMP13 P45452 4/20 0.43
TP53 P04637 2/20 0.41
HSD17B10 Q99714 2/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
MMP3 P08254 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2887982 0.90 LMNA (0.64) LMNAALDH1A1KDM4ECYP3A4GABRB3
Butethal SCHEMBL44262 0.86 LMNA (0.67) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL7348703 0.85 LMNA (0.90) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL3859278 0.85 LMNA (1.00) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL43818 0.85 LMNA (1.00) LMNAALDH1A1KDM4ECYP3A4GABRB3
SCHEMBL918796 0.85 LMNA (0.64) LMNAALDH1A1KDM4ECYP3A4GABRB3
Butethal SCHEMBL2718536 0.85 LMNA (0.64) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL8746543 0.83 LMNA (0.85) LMNAALDH1A1KDM4ECYP3A4GABRB3
SCHEMBL4382583 0.83 MMP9 (0.63) LMNAALDH1A1KDM4ECYP3A4GABRB3
SCHEMBL4379822 0.83 MMP9 (0.63) LMNAALDH1A1KDM4ECYP3A4GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2026-01-15 US disclosed
US-11717549-B2 Steviol glycoside solubility enhancers CARGILL, INCORPORATED (US) 2023-08-08 US disclosed
US-20220323528-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2022-10-13 US disclosed
US-20190223481-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2019-07-25 US disclosed
US-20080104001-A1 ALGORITHM FOR ESTIMATION OF BINDING EQULIBRIA IN INCLUSION COMPLEXATION, HOST COMPOUNDS IDENTIFIED THEREBY AND COMPOSITIONS OF HOST COMPOUND AND PHARMACEUTICAL BAXTER INTERNATIONAL INC. 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS TAS2R7, TAS2R31, TAS2R40 LMNA 4221/4885ALDH1A1 3539/4885KDM4E 3473/4885
US-20220323528-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS SI, TAS2R7, TAS2R31 LMNA 4020/4885ALDH1A1 2625/4885KDM4E 3664/4885
US-11717549-B2 Steviol glycoside solubility enhancers SI, TAS2R7, TAS2R31 LMNA 4020/4885ALDH1A1 2625/4885KDM4E 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.