SCHEMBL2718697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6420147	0.83	HTT (0.43)	HTTALDH1A1NPC1MAPTRAB9A
	SCHEMBL2969264	0.73	THRB (0.48)	THRBTHRAPLK1ALDH1A1KMT2A
	SCHEMBL9861628	0.71	PLK1 (0.64)	THRBTHRAPLK1ALDH1A1KMT2A
	SCHEMBL4904680	0.67	THRB (1.00)	THRBTHRAPLK1ALDH1A1KMT2A
	SCHEMBL2717815	0.66	ALDH1A1 (0.50)	PLK1HTTALDH1A1KMT2AMEN1
	SCHEMBL1483217	0.66	KMT2A (0.64)	THRBTHRAPLK1ALDH1A1KMT2A
	SCHEMBL7218288	0.65	THRB (0.85)	THRBTHRAPLK1ALDH1A1KMT2A
	SCHEMBL4605419	0.65	L3MBTL1 (0.58)	THRBPLK1HTTALDH1A1KMT2A
	Benzophenone SCHEMBL28417175	0.65	L3MBTL1 (0.58)	THRBPLK1HTTALDH1A1KMT2A
	SCHEMBL27449104	0.65	ALDH1A1 (0.64)	THRBPLK1HTTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.