Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EYA2 | O00167 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278283 | 0.88 | TSHR (0.36) | LMNAPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL73690 | 0.81 | EHMT2 (0.37) | LMNAPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1374041 | 0.78 | GCK (0.39) | LMNAPOLBKMT2AMEN1RAB9A | |
| SCHEMBL30392206 | 0.77 | MEN1 (0.41) | LMNAPOLBKMT2AMEN1TSHR | |
| SCHEMBL28384909 | 0.77 | MEN1 (0.41) | LMNAPOLBKMT2AMEN1TSHR | |
| SCHEMBL278282 | 0.76 | GCK (0.39) | LMNAKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL5502675 | 0.76 | LMNA (0.36) | LMNAPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4070360 | 0.73 | LMNA (0.35) | LMNAPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL278281 | 0.72 | LMNA (0.39) | LMNAPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4405681 | 0.71 | GCK (0.40) | LMNAPOLBKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115686-A1 | SHIGELLA MULTI-EPITOPE FUSION ANTIGEN PROTEINS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-04-11 | — | — | US | disclosed |