SCHEMBL4070360

SCHEMBL4070360

CCc1ccc(SSc2ccccn2)cc1C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
EHMT2 Q96KQ7 1/20 0.35
EHMT1 Q9H9B1 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
RAB9A P51151 3/20 0.34
ALDH1A1 P00352 3/20 0.34
POLB P06746 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MAPK10 P53779 1/20 0.33
NPC1 O15118 1/20 0.33
GCK P35557 2/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1374041 0.91 GCK (0.39) LMNARAB9AALDH1A1POLBGCK
SCHEMBL5502675 0.82 LMNA (0.36) LMNAEHMT2EHMT1APOBEC3GRAB9A
SCHEMBL1679370 0.82 EHMT2 (0.35) LMNAEHMT2EHMT1APOBEC3GRAB9A
SCHEMBL561821 0.82 RAB9A (0.37) LMNAEHMT2EHMT1APOBEC3GRAB9A
SCHEMBL11122105 0.80 EHMT2 (0.39) EHMT2EHMT1APOBEC3GRAB9AALDH1A1
SCHEMBL8328957 0.78 ALDH1A1 (0.39) LMNARAB9AALDH1A1POLBSMN1; SMN2
SCHEMBL28514925 0.78 LMNA (0.45) LMNAEHMT2EHMT1APOBEC3GRAB9A
SCHEMBL1746858 0.77 ALDH1A1 (0.35) LMNAEHMT2EHMT1APOBEC3GRAB9A
SCHEMBL4184231 0.76 MEN1 (0.37) LMNAEHMT2EHMT1APOBEC3GRAB9A
SCHEMBL73690 0.76 EHMT2 (0.37) LMNAEHMT2EHMT1APOBEC3GRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149534-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS BIOVAXYS LLC 2023-05-18 US disclosed
WO-2023060220-A1 METHODS OF IMMUNIZATION AGAINST CORONAVIRUS BioVaxys Inc. (US) 2023-04-13 WO disclosed
EP-4121103-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS BioVaxys Inc. (US) 2023-01-25 EP disclosed
WO-2021188991-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS BioVaxys Inc. (US) 2021-09-23 WO disclosed
US-20140113371-A1 Cryopreservation of Haptenized Tumor Cells BERD DAVID (US) 2014-04-24 US disclosed
US-8435784-B2 Cryopreservation of haptenized tumor cells THOMAS JEFFERSON UNIVERSITY 2013-05-07 US disclosed
EP-1581242-A4 COMPOSITIONS AND METHODS FOR MODIFYING TOXIC EFFECTS OF PROTEINACEOUS COMPOUNDS UNIV TEXAS (US) 2009-06-24 EP disclosed
US-20070237795-A1 Cryopreservation of Haptenized Tumor Cells AVAX TECHNOLOGIES, INC. 2007-10-11 US disclosed
US-20050233301-A1 Cryopreservation of haptenized tumor cells BERD DAVID 2005-10-20 US disclosed
EP-1581242-A2 COMPOSITIONS AND METHODS FOR MODIFYING TOXIC EFFECTS OF PROTEINACEOUS COMPOUNDS BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 2005-10-05 EP disclosed
EP-1551225-A2 CRYOPRESERVATION OF HAPTENIZED TUMOR CELLS Avax Technologies Inc. (US) 2005-07-13 EP disclosed
WO-2004040262-A2 COMPOSITIONS AND METHODS FOR MODIFYING TOXIC EFFECTS OF PROTEINACEOUS COMPOUNDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2004-05-13 WO disclosed
WO-2003103389-A2 CRYOPRESERVATION OF HAPTENIZED TUMOR CELLS AVAX TECHNOLOGIES INC. (US) 2003-12-18 WO disclosed
US-5767072-A Therapeutic compositions comprising a CD4 peptide and methods of treatment of HIV infections BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1998-06-16 US disclosed
US-5578706-A Methods and compositions concerning homogenous immunotoxin preparations BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) 1996-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149534-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS ACE2, CD14, TMPRSS2 LMNA 4605/4885EHMT2 2542/4885EHMT1 3202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.