SCHEMBL2719444

SCHEMBL2719444

Cc1ccc(OCC(=O)N(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.71
▸ GAA P10253 2/20 0.71
▸ TRPM8 Q7Z2W7 4/20 0.70
▸ MEN1 O00255 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ HTT P42858 2/20 0.58
▸ NPC1 O15118 2/20 0.57
▸ RAB9A P51151 2/20 0.57
▸ LTB4R2 Q9NPC1 1/20 0.57
▸ MAPK1 P28482 1/20 0.56
▸ CNR2 P34972 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ GLA P06280 1/20 0.54
▸ PAX8 Q06710 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2717555 0.91 GAA (0.67) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL19141832 0.86 GAA (0.58) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL17230201 0.84 TRPM8 (0.64) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL2717047 0.82 TRPM8 (1.00) TRPM8
SCHEMBL2717345 0.82 TRPM8 (0.71) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL23126349 0.82 SMN1; SMN2 (0.53) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL2717321 0.81 TRPM8 (0.70) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL2720389 0.81 TRPM8 (0.70) SMN1; SMN2GAATRPM8
SCHEMBL2720161 0.81 TRPM8 (0.70) SMN1; SMN2GAATRPM8MEN1KMT2A
SCHEMBL20777298 0.81 TRPM8 (0.60) SMN1; SMN2GAATRPM8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 — — WO disclosed
CN-118697922-A Perfume dispersing device 弗门尼舍有限公司 2024-09-27 — — CN disclosed
EP-3470407-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2024-01-24 — — EP disclosed
CN-109414048-B Coated yeast formulation 弗门尼舍有限公司 2023-09-01 — — CN disclosed
US-11234450-B2 Preparations having a cooling effect SYMRISE AG (DE) 2022-02-01 — — US disclosed
EP-3478089-B1 PLATED YEAST FORMULATIONS FIRMENICH & CIE (CH) 2021-11-03 — — EP disclosed
US-11160894-B2 Perfume emanating device FIRMENICH SA (CH) 2021-11-02 — — US disclosed
US-11091734-B2 Plated yeast formulations FIRMENICH SA (CH) 2021-08-17 — — US disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 — — US disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 — — US disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 — — US disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 — — US disclosed
US-20150313820-A1 PREPARATIONS SYMRISE AG (DE) 2015-11-05 — — US disclosed
US-20150313820-A1 PREPARATIONS SYMRISE AG (DE) 2015-11-05 — — US disclosed
US-20130324557-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2013-12-05 — — US disclosed
EP-2635572-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2013-09-11 — — EP disclosed
WO-2012061698-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-09-13 — — WO disclosed
WO-2012061698-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-09-13 — — WO disclosed
WO-2012061698-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-05-10 — — WO disclosed
WO-2012061698-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-05-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160894-B2 Perfume emanating device DPM1, SURF4, FAAH2 SMN1; SMN2 4203/4885GAA 4602/4885TRPM8 151/4885
US-10953007-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM7, TRPM6 SMN1; SMN2 2789/4885GAA 3113/4885TRPM8 1/4885
US-11234450-B2 Preparations having a cooling effect CRAT, CPT2, CPT1A SMN1; SMN2 528/4885GAA 1067/4885TRPM8 60/4885
US-20130324557-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM7, TRPM6 SMN1; SMN2 2789/4885GAA 3113/4885TRPM8 1/4885
US-20150313820-A1 PREPARATIONS CRAT, ACAT2, TAS2R50 SMN1; SMN2 1059/4885GAA 1009/4885TRPM8 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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