SCHEMBL2719458

SCHEMBL2719458

CO[Si](OC)(OC)C(Cc1ccccc1)C(N)CCN

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
SLC6A2 P23975 2/20 0.42
TAAR1 Q96RJ0 2/20 0.42
MAOA P21397 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
CYP2A6 P11509 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
EPHX1 P07099 1/20 0.40
CYP2D6 P10635 1/20 0.40
LAP3 P28838 1/20 0.39
CSNK1E P49674 1/20 0.37
ANPEP P15144 2/20 0.37
HRH1 P35367 1/20 0.35
ALPI P09923 1/20 0.35
PKM P14618 1/20 0.35
PTGS1 P23219 1/20 0.35
XIAP P98170 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15453594 0.86 ALDH1A1 (0.44) ALDH1A1SLC6A2TAAR1MAOASLC6A4
SCHEMBL4590844 0.85 ALDH1A1 (0.40) ALDH1A1SLC6A2TAAR1MAOASLC6A4
SCHEMBL16739238 0.84 ANPEP (0.36) ALDH1A1SLC6A2TAAR1MAOASLC6A4
SCHEMBL3476725 0.80 CYP2D6 (0.53) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL614445 0.79 ALDH1A1 (0.49) ALDH1A1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2719462 0.78 CYP2D6 (0.50) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL613425 0.76 EPHX1 (0.46) ALDH1A1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2488884 0.74 SLC6A2 (0.52) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL447453 0.74 SIGMAR1 (0.44) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL339199 0.74 SIGMAR1 (0.47) SLC6A2TAAR1MAOASLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916541-B2 Immobilization Dna, nucleic acid; hybrid analyzing PENN STATE RESEARCH FOUNDATION (US) 2005-07-12 US claimed
US-20050064209-A1 Low-fluorescent, chemically durable hydrophobic patterned substrates for the attachment of biomolecules HAINES DANIEL (US) 2005-03-24 US claimed
WO-2003022769-A9 MODIFIED SUBSTRATES FOR THE ATTACHMENT OF BIOMOLECULES PENN STATE RES FOUND (US) 2004-05-06 WO claimed
US-20030054176-A1 Modified substrates for the attachment of biomolecules PENN STATE RESEARCH FOUNDATION 2003-03-20 US claimed
WO-2003022769-A1 MODIFIED SUBSTRATES FOR THE ATTACHMENT OF BIOMOLECULES THE PENN STATE RESEARCH FOUNDATION (US) 2003-03-20 WO claimed
US-20020197481-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2002-12-26 US claimed
US-11285171-B2 Nitric oxide releasing suppositories and methods of use thereof NOVAN, INC. (US) 2022-03-29 US disclosed
US-20200397815-A1 NITRIC OXIDE RELEASING SUPPOSITORIES AND METHODS OF USE THEREOF LIGAND PHARMACEUTICALS INCORPORATED 2020-12-24 US disclosed
US-10259208-B2 Three-dimensional shaped object manufacturing device, method for manufacturing three-dimensional shaped object, and three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2019-04-16 US disclosed
US-9732204-B2 Ultraviolet ray curable ink composition for use in ink jet method and printed object SEIKO EPSON CORPORATION (JP) 2017-08-15 US disclosed
US-9630339-B2 Manufacturing method of three-dimensional structure and three-dimensional structure SEIKO EPSON CORPORATION (JP) 2017-04-25 US disclosed
US-9579852-B2 Method for manufacturing three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2017-02-28 US disclosed
US-9528019-B2 Ultraviolet-curable inkjet composition and material SEIKO EPSON CORPORATION (JP) 2016-12-27 US disclosed
US-20050277145-A1 Apparatus with microtiter plate format for multiplexed arraying HAINES DAN 2005-12-15 US disclosed
EP-1600213-A1 Apparatus with microtiter plate format for multiplexed arraying SCHOTT AG (DE) 2005-11-30 EP disclosed
US-6916541-B2 Immobilization Dna, nucleic acid; hybrid analyzing PENN STATE RESEARCH FOUNDATION (US) 2005-07-12 US disclosed
US-20050064209-A1 Low-fluorescent, chemically durable hydrophobic patterned substrates for the attachment of biomolecules HAINES DANIEL (US) 2005-03-24 US disclosed
WO-2003022769-A9 MODIFIED SUBSTRATES FOR THE ATTACHMENT OF BIOMOLECULES PENN STATE RES FOUND (US) 2004-05-06 WO disclosed
US-20030054176-A1 Modified substrates for the attachment of biomolecules PENN STATE RESEARCH FOUNDATION 2003-03-20 US disclosed
WO-2003022769-A1 MODIFIED SUBSTRATES FOR THE ATTACHMENT OF BIOMOLECULES THE PENN STATE RESEARCH FOUNDATION (US) 2003-03-20 WO disclosed