SCHEMBL339199

SCHEMBL339199

CCNC(N)C(Cc1ccccc1)[Si](OC)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.47
SLC6A2 P23975 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
MAOA P21397 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
EPHX1 P07099 1/20 0.39
CYP2D6 P10635 1/20 0.39
LAP3 P28838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340569 0.87 SIGMAR1 (0.46) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL3476725 0.79 CYP2D6 (0.53) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2719462 0.76 CYP2D6 (0.50) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL447453 0.76 SIGMAR1 (0.44) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2719458 0.74 ALDH1A1 (0.46) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2488884 0.73 SLC6A2 (0.52) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL1730609 0.73 TAAR1 (0.50) SIGMAR1SLC6A2TAAR1MAOASLC6A4
Benzylamine SCHEMBL5533155 0.70 LOXL2 (0.42) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL37760 0.70 SIGMAR1 (0.44) SIGMAR1SLC6A2TAAR1MAOASLC6A4
Benzylamine SCHEMBL28373205 0.70 SIGMAR1 (0.44) SIGMAR1SLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11975091-B2 Composition for enhancing protein strength LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2024-05-07 US claimed
US-10196349-B2 Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2019-02-05 US claimed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US claimed
US-20070286994-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US claimed
US-10322082-B2 Topical antiviral compositions and methods of using the same NOVAN, INC. (US) 2019-06-18 US disclosed
US-9919072-B2 Wound dressings, methods of using the same and methods of forming the same NOVAN, INC. (US) 2018-03-20 US disclosed
US-20180008533-A1 TOPICAL ANTIVIRAL COMPOSITIONS AND METHODS OF USING THE SAME LIGAND PHARMACEUTICALS INCORPORATED 2018-01-11 US disclosed
US-9737561-B2 Topical gels and methods of using the same NOVAN, INC. (US) 2017-08-22 US disclosed
US-20170056437-A1 TOPICAL GELS AND METHODS OF USING THE SAME LIGAND PHARMACEUTICALS INCORPORATED 2017-03-02 US disclosed
US-9526738-B2 Topical gels and methods of using the same NOVAN, INC. (US) 2016-12-27 US disclosed
EP-2539394-B1 RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS BRIDGESTONE CORP (JP) 2014-11-19 EP disclosed
US-8591876-B2 Methods of decreasing sebum production in the skin NOVAN, INC. (US) 2013-11-26 US disclosed
US-20100239776-A1 METHOD FOR PRODUCING PLASTIC LENS HOYA CORPORATION (JP) 2010-09-23 US disclosed
US-20100232021-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2010-09-16 US disclosed
US-7537828-B2 Low refractive index composition comprising fluoropolyether urethane compound 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-05-26 US disclosed
US-20080240479-A1 HYDROPHOBIC AND OLEOPHOBIC COATING AND METHOD FOR PREPARING THE SAME SONIC INNOVATIONS, INC. 2008-10-02 US disclosed
US-20070286994-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US disclosed
US-20070286992-A1 LOW REFRACTIVE INDEX COMPOSITION COMPRISING FLUOROPOLYETHER URETHANE COMPOUND 3M INNOVATION PROPERTIES COMPANY 2007-12-13 US disclosed
US-20070285778-A1 OPTICAL FILMS COMPRISING HIGH REFRACTIVE INDEX AND ANTIREFLECTIVE COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US disclosed
US-20070285779-A1 OPTICAL FILMS COMPRISING HIGH REFRACTIVE INDEX AND ANTIREFLECTIVE COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11975091-B2 Composition for enhancing protein strength CUTA, S100A4, S100A8 SIGMAR1 2831/4885SLC6A2 4119/4885TAAR1 1760/4885
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN SIGMAR1 673/4885SLC6A2 3196/4885TAAR1 4128/4885
US-10196349-B2 Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures NOS2, NOS3, NOS1 SIGMAR1 871/4885SLC6A2 532/4885TAAR1 577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.