Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18603423 | 0.84 | P2RY2 (0.31) | P2RY2P2RY4 | |
| SCHEMBL272685 | 0.78 | P2RY2 (0.32) | P2RY2P2RY4 | |
| SCHEMBL272356 | 0.76 | P2RY2 (0.42) | P2RY2P2RY4P2RY6 | |
| SCHEMBL271982 | 0.74 | P2RY2 (0.39) | ALDH1A1P2RY2P2RY4P2RY6 | |
| SCHEMBL271939 | 0.72 | P2RY2 (0.33) | P2RY2P2RY4P2RY6 | |
| SCHEMBL271983 | 0.72 | P2RY2 (0.36) | ALDH1A1P2RY2P2RY4P2RY6KDM4E | |
| SCHEMBL272343 | 0.71 | P2RY2 (0.36) | ALDH1A1P2RY2P2RY4P2RY6 | |
| SCHEMBL272500 | 0.70 | P2RX3 (0.43) | P2RY2P2RY4P2RY6 | |
| SCHEMBL272498 | 0.68 | P2RY2 (0.36) | ALDH1A1P2RY2P2RY4P2RY6 | |
| SCHEMBL28311702 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133669-B2 | Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid | TRILINK BIOTECHNOLOGIES (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100003724-A1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID | TriLink Bio Technologies | 2010-01-07 | — | — | US | disclosed |