Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549463 | 0.83 | TRPM8 (0.46) | TRPM8TRPV1 | |
| SCHEMBL25005229 | 0.83 | KDM1A (0.58) | TRPM8TRPV1KDM1AMAOAMAOB | |
| SCHEMBL8202664 | 0.82 | ALDH1A1 (0.39) | TRPM8TRPV1KDM1A | |
| SCHEMBL8498806 | 0.82 | TRPA1 (0.43) | TRPM8TRPV1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL9737051 | 0.82 | TRPA1 (0.43) | TRPM8TRPV1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL5194290 | 0.81 | TRPM8 (0.42) | TRPM8TRPV1 | |
| SCHEMBL5824340 | 0.81 | ESR2 (0.49) | TRPM8TRPV1KDM1A | |
| SCHEMBL6378310 | 0.81 | TRPM8 (0.42) | TRPM8TRPV1 | |
| SCHEMBL3639819 | 0.80 | KCNA5 (0.53) | TRPM8TRPV1KDM1AMAOAMAOB | |
| SCHEMBL562415 | 0.79 | HPGD (0.50) | TRPM8TRPV1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | SANOFI (FR) | 2024-04-18 | — | — | US | disclosed |
| CN-116685300-A | Composition comprising one or more (bio) -alkanediols with an antioxidant | 西姆莱斯股份公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-104812373-B | Mouth gel for sensibility and dental pain | 高露洁-棕榄公司 | 2019-01-08 | — | — | CN | disclosed |
| CN-104837481-B | Mouth gel for mitigating dental pain | 高露洁-棕榄公司 | 2017-11-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | TRPM8, TAS2R8, TRPM7 | TRPM8 1/4885TRPV1 14/4885KDM1A 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.