SCHEMBL2719940

SCHEMBL2719940

O=C(CCCCl)Cc1ccccc1F

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 1/20 0.48
ALDH1A1 P00352 7/20 0.43
MAPK1 P28482 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPK8 P45983 1/20 0.40
LMNA P02545 2/20 0.40
RAB9A P51151 1/20 0.40
GLS O94925 1/20 0.39
MAOB P27338 2/20 0.39
PARP15 Q460N3 1/20 0.39
PARP14 Q460N5 1/20 0.39
PARP10 Q53GL7 1/20 0.39
CASP3 P42574 1/20 0.38
CASP7 P55210 1/20 0.38
CXCL8 P10145 2/20 0.38
SIGMAR1 Q99720 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2717117 0.83 VNN1 (0.45) VNN1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL1538027 0.83 VNN1 (0.48) VNN1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL3013122 0.82 ALDH1A1 (0.46) VNN1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL4661911 0.81 ALDH1A1 (0.51) VNN1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL6225369 0.81 CTBP2 (0.47) ALDH1A1KMT2AMAPK8RAB9AGLS
SCHEMBL6222569 0.79 MAPK8 (0.40) ALDH1A1KMT2AMAPK8LMNARAB9A
SCHEMBL8204011 0.79 VNN1 (0.45) VNN1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL8677157 0.79 VNN1 (0.50) VNN1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL11078708 0.76 MMP2 (0.37) VNN1
Methylene Chloride SCHEMBL28534416 0.74 ALDH1A1 (0.48) ALDH1A1MAPK1MEN1KMT2AMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2123656-B1 PROCESS FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY DAIICHI SANKYO CO LTD (JP) 2014-06-11 EP disclosed
US-20130345428-A1 METHOD FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY UBE INDUSTRIES, LTD. (JP) 2013-12-26 US disclosed
WO-2012052788-A1 METHOD FOR PREPARING PHARMACEUTICALLY ACTIVE INGREDIENT AND INTERMEDIATES THEREOF EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MŰKÖDŐ RÉSZVÉNYTÁRSASÁG (HU) 2012-04-26 WO disclosed
US-20100094013-A1 PROCESS FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY DAIICHI SANKYO COMPANY, LIMITED (JP) 2010-04-15 US disclosed
EP-2123656-A1 PROCESS FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY Daiichi Sankyo Company, Limited (JP) 2009-11-25 EP disclosed
EP-1411942-A4 SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS SYNAPTIC PHARMA CORP (US) 2005-01-26 EP disclosed
EP-1411942-A1 SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS Synaptic Pharmaceutical Corporation (US) 2004-04-28 EP disclosed
WO-2003004027-A1 SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2003-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094013-A1 PROCESS FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY AGPS, CAT, PFKP VNN1 2176/4885ALDH1A1 435/4885MAPK1 3172/4885
US-20130345428-A1 METHOD FOR PRODUCTION OF PRASUGREL HYDROCHLORIDE HAVING HIGH PURITY PFKP, PF4, POR VNN1 1509/4885ALDH1A1 476/4885MAPK1 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.