Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366364 | 0.79 | ACHE (0.42) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL27199799 | 0.71 | ACHE (0.50) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL2222493 | 0.71 | MAPT (0.47) | ACHEMAPTPARP1KDM4EMEN1 | |
| SCHEMBL29642993 | 0.69 | ACHE (0.78) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL972999 | 0.69 | ACHE (0.78) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL9316093 | 0.68 | ACHE (0.59) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL27136670 | 0.67 | ACHE (0.53) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL27092615 | 0.66 | ACHE (0.47) | GABRA1GABRG2GABRB3GABRA3ACHE | |
| SCHEMBL1051873 | 0.65 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL13100680 | 0.64 | KIF11 (0.62) | GABRA1GABRG2GABRB3GABRA3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |