Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NAT1 | P18440 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200652 | 0.81 | PRMT6 (0.46) | PTGES2CA1CA2NAT1HTR7 | |
| SCHEMBL29264249 | 0.80 | HTR7 (0.47) | PTGES2CA1CA2HTR7SCN9A | |
| SCHEMBL29264198 | 0.80 | CA2 (0.42) | PTGES2CA1CA2HTR7SCN9A | |
| SCHEMBL27200808 | 0.80 | PRMT6 (0.48) | CA1CA2HTR7SCN9AHTR1A | |
| SCHEMBL29264216 | 0.79 | CSNK2A2 (0.42) | CA1CA2HTR7CSNK2A1SCN9A | |
| SCHEMBL29264203 | 0.79 | HTR7 (0.40) | PTGES2CA1CA2HTR7SCN9A | |
| SCHEMBL29264247 | 0.79 | HTR7 (0.48) | PTGES2CA1CA2HTR7CSNK2A1 | |
| SCHEMBL27200641 | 0.77 | HTR7 (0.38) | CA1CA2HTR7SCN9AHTR1A | |
| SCHEMBL29264212 | 0.77 | SCN9A (0.41) | PTGES2CA1CA2HTR7SCN9A | |
| SCHEMBL29264253 | 0.77 | HTR7 (0.64) | PTGES2CA1CA2HTR7SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4357338-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | Shanghai Leado Pharmatech Co. Ltd. (CN) | 2024-04-24 | — | — | EP | disclosed |