Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202066 | 0.90 | ALDH1A1 (0.51) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL27202055 | 0.87 | HTR6 (0.50) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL27261095 | 0.87 | ADRB1 (0.42) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL27202084 | 0.82 | ALDH1A1 (0.49) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL5745223 | 0.79 | ADRB1 (0.49) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL4359282 | 0.79 | ADRB1 (0.42) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL27207483 | 0.78 | CYP3A4 (0.46) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL27202089 | 0.78 | ALDH1A1 (0.50) | ALDH1A1USP2TSHRHSD17B10HTR6 | |
| SCHEMBL27862034 | 0.78 | TTR (0.41) | ALDH1A1HSD17B10TTRKDM4EHPGD | |
| SCHEMBL27844239 | 0.75 | POLB (0.41) | ALDH1A1TSHRHSD17B10TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | ALDH1A1 446/4885USP2 3092/4885TSHR 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.