Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CBR1 | P16152 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30350005 | 0.93 | STS (0.34) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL28977517 | 0.93 | STS (0.34) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL24240022 | 0.93 | STS (0.34) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL24240023 | 0.83 | ITGB3 (0.33) | SRD5A1SRD5A2 | |
| SCHEMBL24240040 | 0.74 | MAPT (0.36) | SRD5A1SRD5A2TP53POLB | |
| SCHEMBL24240017 | 0.68 | MIF (0.51) | STSSRD5A1SRD5A2PTPN7TP53 | |
| SCHEMBL25997466 | 0.63 | RAB9A (0.37) | TP53POLB | |
| SCHEMBL25438806 | 0.62 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL30350030 | 0.60 | MAOB (0.54) | AKR1B1TP53POLB | |
| SCHEMBL24239998 | 0.60 | MAOB (0.54) | AKR1B1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981964-B2 | Substituted coumarin dyes and uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981964-B2 | Substituted coumarin dyes and uses as fluorescent labels | FBL, DUT, PHAX | AKR1B10 1273/4885AKR1B1 1231/4885AKR1A1 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.