Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753915 | 0.80 | NAAA (0.48) | MAPTALDH1A1ARKDM4ELMNA | |
| SCHEMBL30373808 | 0.80 | ALDH1A1 (0.71) | MAPTGAATDP1MEN1MITF | |
| SCHEMBL9139876 | 0.80 | ALDH1A1 (0.71) | MAPTGAATDP1MEN1MITF | |
| SCHEMBL15471933 | 0.79 | ALDH1A1 (0.68) | MAPTGAATDP1MEN1MITF | |
| SCHEMBL15471934 | 0.79 | KDM4E (0.44) | MAPTGAATDP1MEN1MITF | |
| SCHEMBL15471931 | 0.79 | ALDH1A1 (0.44) | MAPTGAATDP1MEN1MITF | |
| SCHEMBL1974542 | 0.78 | ALDH1A1 (0.48) | MAPTGAATDP1MEN1MITF | |
| SCHEMBL30887951 | 0.78 | P2RX1 (0.60) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL2170423 | 0.78 | P2RX1 (0.60) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL17185444 | 0.78 | ALDH1A1 (0.44) | MAPTGAATDP1MEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051708-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES, AND METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-04-26 | — | — | WO | disclosed |