Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723700 | 0.77 | KDM4E (0.59) | KDM4EGLATDP1NPC1RAB9A | |
| SCHEMBL17950444 | 0.75 | KDM4E (0.50) | KDM4EGLATDP1NPC1RAB9A | |
| SCHEMBL2722158 | 0.73 | KMT2A (0.58) | KDM4EGLATDP1NPC1RAB9A | |
| SCHEMBL6922909 | 0.72 | MAPK1 (0.51) | KDM4EGLATDP1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL27553000 | 0.71 | KDM4E (0.46) | KDM4EGLATDP1NPC1RAB9A | |
| SCHEMBL2117475 | 0.70 | ALDH1A1 (0.54) | KDM4ETDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL31483762 | 0.70 | PARP14 (0.44) | KDM4EGLAALDH1A1 | |
| SCHEMBL2723566 | 0.70 | KDM4E (0.49) | KDM4EGLATDP1NPC1RAB9A | |
| SCHEMBL30507791 | 0.69 | KDM4E (0.50) | KDM4EGLATDP1NPC1RAB9A | |
| SCHEMBL2118762 | 0.69 | ALDH1A1 (0.55) | KDM4ETDP1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |