Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680130 | 0.82 | KDM1A (0.48) | SIGMAR1TMEM97KDM1A | |
| SCHEMBL26984159 | 0.82 | KDM1A (0.48) | SIGMAR1TMEM97KDM1A | |
| SCHEMBL27223534 | 0.82 | ELANE (0.40) | SIGMAR1TMEM97KDM1A | |
| SCHEMBL27223441 | 0.79 | PARP1 (0.46) | SIGMAR1TMEM97 | |
| SCHEMBL2124213 | 0.78 | NPSR1 (0.48) | KDM1A | |
| SCHEMBL30749278 | 0.77 | TSHR (0.35) | SIGMAR1TMEM97 | |
| SCHEMBL27223617 | 0.77 | TSHR (0.35) | SIGMAR1TMEM97 | |
| SCHEMBL18065031 | 0.77 | SMN1; SMN2 (0.49) | KDM1A | |
| SCHEMBL28856757 | 0.77 | SMN1; SMN2 (0.46) | KDM1A | |
| SCHEMBL30749360 | 0.77 | MPO (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-05-23 | — | — | US | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | MPO, XDH, EPX | SIGMAR1 937/4885TMEM97 3555/4885KDM1A 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.