Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223617 | 1.00 | TSHR (0.35) | TSHRL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL27223561 | 0.81 | PARP1 (0.40) | L3MBTL1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30749244 | 0.81 | PARP1 (0.40) | L3MBTL1KMT2APDK1PDK2PDK3 | |
| SCHEMBL27223650 | 0.79 | ALDH1A1 (0.32) | L3MBTL1SIGMAR1TMEM97LMNA | |
| SCHEMBL30749220 | 0.79 | ALDH1A1 (0.32) | L3MBTL1SIGMAR1TMEM97LMNA | |
| SCHEMBL30749232 | 0.78 | RECQL (0.36) | L3MBTL1 | |
| SCHEMBL27223628 | 0.78 | RECQL (0.36) | L3MBTL1 | |
| SCHEMBL27223485 | 0.77 | SIGMAR1 (0.43) | SIGMAR1TMEM97 | |
| SCHEMBL27224058 | 0.76 | ALDH1A1 (0.39) | KMT2ARAB9AKDM4EMEN1 | |
| SCHEMBL27224168 | 0.75 | ALOX15 (0.39) | KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |