SCHEMBL27223520

SCHEMBL27223520

C=CCOCc1ccc(Cl)cc1C1COCCN1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 1/20 0.30
▸ SLC5A2 P31639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27224065 0.72 ALDH1A1 (0.35) —
SCHEMBL31444529 0.70 HTR2A (0.40) —
SCHEMBL14833093 0.70 HTR2C (0.50) —
SCHEMBL27223381 0.69 TSHR (0.41) —
SCHEMBL31556702 0.68 MGLL (0.43) —
SCHEMBL27224135 0.66 TSHR (0.41) —
Hydrochloric Acid SCHEMBL27232296 0.65 TSHR (0.40) SLC5A1SLC5A2
SCHEMBL27223582 0.64 GAA (0.36) —
SCHEMBL17495041 0.64 TDP1 (0.44) —
SCHEMBL2944138 0.64 CHRNA7 (0.47) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573096-A1 INHIBITORS OF MYELOPEROXIDASE Astrazeneca AB (SE) 2025-06-25 — — EP disclosed
CN-119894896-A Inhibitors of green peroxidase 阿斯利康(瑞典)有限公司 2025-04-25 — — CN disclosed
US-20240166642-A1 INHIBITORS OF MYELOPEROXIDASE ASTRAZENECA AB (SE) 2024-05-23 — — US disclosed
WO-2024038131-A1 INHIBITORS OF MYELOPEROXIDASE ASTRAZENECA AB (SE) 2024-02-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166642-A1 INHIBITORS OF MYELOPEROXIDASE MPO, XDH, EPX SLC5A1 1198/4885SLC5A2 1245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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