Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723008 | 0.81 | TGM2 (0.53) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL2723976 | 0.77 | P2RX7 (0.40) | P2RX7ALDH1A1TDP1LMNAKMT2A | |
| SCHEMBL8766077 | 0.77 | TGM2 (0.47) | TGM2P2RX7ALDH1A1TSHRMAPK1 | |
| SCHEMBL1025173 | 0.75 | TGM2 (0.45) | TGM2P2RX7ALDH1A1TSHRMAPK1 | |
| SCHEMBL28987058 | 0.73 | TGM2 (0.44) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL5082541 | 0.70 | KMT2A (0.67) | TGM2ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL27978119 | 0.70 | ALDH1A1 (0.41) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL959540 | 0.69 | TGM2 (0.69) | TGM2ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL4927519 | 0.69 | TGM2 (0.69) | TGM2ALDH1A1TDP1LMNAGAA | |
| SCHEMBL28987062 | 0.69 | TSHR (0.43) | TGM2ALDH1A1TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | claimed |
| US-10023782-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170335162-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | HERCULES LLC | 2017-11-23 | — | — | US | disclosed |
| US-9611416-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20130324443-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2013-12-05 | — | — | US | disclosed |
| WO-2013162902-A1 | SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER | ISP INVESTMENTS INC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013138156-A1 | SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER | ISP INVESTMENTS INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012061147-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | disclosed |